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Another randomized-placebo controlled study failed to find improvements in any glycemia control marker in therapy-naïve DM patients undergoing a 28-day therapy with eight daily capsules of either MO (4 g/d) or placebo [22].A non-significant reduction of 3–4% of initial values was found in HbA1c as compared to baseline in both treatment arms, which reflected that self-monitoring plasma glucose provides feedback that improves glycemic control through lifestyle changes

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Contrave side effects can include constipation, dizziness, headache, trouble sleeping, and upset stomach